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To investigate the effect of hydrodynamic stress on the optic-corneal interface. Department of Ophthalmology, Tokai University School of Medicine Methods: We used an experimental model to investigate the effect of hydrodynamic stress on the optic-corneal interface. We used a fluid-dynamic analysis to simulate different hydrodynamic states. We compared the hydraulic pressure on the optic-corneal interface when the vitreous humor pressure was changed under normal and hydrodynamic states. Pressure was measured using a pressure sensor. We placed a 6.0-mm-diameter optic on a 0.5-mm-thick thin plate of PMMA (polymethyl methacrylate). We calculated the hydraulic pressure on the surface of the optic based on the vitreous humor pressure using a fluid-dynamic analysis. We investigated the effect of hydrodynamic stress on the optic-corneal interface when the hydraulic pressure was changed. In the normal state, the hydraulic pressure on the surface of the optic reached 2.
An accelerated-testing methodology has been developed for measuring the slow-crack-growth (SCG) behavior of brittle materials. Like the prior methodology, the accelerated-testing methodology involves dynamic fatigue ( constant stress-rate) testing, in which a load or a displacement is applied to a specimen at a constant rate. SCG parameters or life prediction parameters needed for designing components made of the same material as that of the specimen are calculated from the relationship between (1) the strength of the material as measured in the test and (2) the applied stress rate used in the test. Despite its simplicity and convenience, dynamic fatigue testing as practiced heretofore has one major drawback: it is extremely time-consuming, especially at low stress rates. The present accelerated methodology reduces the time needed to test a specimen at a given rate of applied load, stress, or displacement. Instead of starting the test from zero applied load or displacement as in the prior methodology, one preloads the specimen and increases the applied load at the specified rate (see Figure 1). One might expect the preload to alter the results of the test and indeed it does, but fortunately, it is possible to account for the effect of the preload in interpreting the results.
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